Devine is located on old US 81, I-35, and Hwy 173, thirty miles southwest of
San Antonio in southeast
Medina County.
It is the site of the largest Spanish peanut shipping center in South Texas. Among its other prominent businesses are Texas Tire Test Fleet, Levans Manufacturing Company that makes women's undergarments, two banks, a farmer's co-op, two weekly newspapers, and two feedlots.
Devine had a population of 3,928 in 1990.
