Memphis is located southeast of Amarillo
along US 287 near the Prairie Dog Town Fork of the Red River
, where it is the seat of Hall County
Since the Great Depression era Memphis has continued as a farm supply center. In 1986 the city had a cotton compress, gins, a grain elevator, two banks, eight churches, four public schools, a modern medical complex, two motels, and several mercantile stores.
The route of the annual Cotton Boll Enduro, a 125-mile cross country motorcycle event held in late October, begins and ends at Memphis.
In 1990 Memphis had a population of 2,465.