Henderson is located in York County off of I-80, east of Grand Island, between Aurora and York. Henderson is part of the Grand Island Metro area.
The population estimate for July 1, 1998 was 990, a decrease of 9 since 1990.
Mennonite immigrants bought land from the Burlington and Missouri River Railroad. With a helping hand, the R. R. Company erected an immigrant house which provided shelter until individual homes were built. Its location is designated by a commemorative marker one mile east of this site. By 1878 approximately eighty families lived in the settlement, and a town established in 1887 was named in honor of David Henderson, an earlier homesteader from Holland.
Today, Henderson is mainly a commuter town for Grand Island and other more-populated areas.