Hyannis is located in Grant County (of which it is the county seat), east of Alliance, between Ashby and Whitman along Hwy 2 and the main line of the Burlington , Northern and Santa Fe Railroad, near George Lake.
The population estimate for July 1, 1998 was 208, a decrease of 2 since 1990.
Hyannis Nebraska, founded in 1887, by Anselmo B. Smith a civil engineer that worked for the railroad company, he named it for Hyannis, Massachusetts where he had grown up.
Hyannis has several businesses within it's limits including repair shops, 2 banks, veterinary service, grocery store, lumber yard, flower shop, family doctor, and a newly remodeled hotel that is still situated in it's original building, built in 1898. During the hotel's early life, it was the "Home Away from Home" for most of the cattlemen that came to town to ship their live stock to Omaha and St. Joseph, Missouri.