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Syracuse is located in Otoe County between Lincoln and Nebraska City along Hwy 2 and near the Little Nemaha River. Syracuse is part of the Lincoln, Nebraska Metropalitan Area.

The population estimate for July 1, 1998 was 1,697, an increase of 51 since 1990.

The name appears at a site southeast of Unadilla in 1856, nearly six miles west of its present location where salt was discovered. The first root for the present town of Syracuse was planted in the late 1850s when a school was established.

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08/08 Coming to The area
Jefferson Bell Tower Festival Jefferson IA June7-8 Jefferson's annual Festival promises a weekend full of family-friendly fun and entertainment. Nestled in the middle of Greene County's county seat, the Festival is home to a broad spectrum of activities.
Swedish Festival Stromberg NE June14-16 Welcome to Stromsberg, the Swede capital of Nebraska. Swedish dancing, costumes, and food can be enjoyed throughout the festivities.
Glenn Miller Festival Clarinda IA June13-16 Hear exciting bands from around the world topped off by the World Famous Glenn Miller Orchestra. Enjoy the new Glenn Miller Birthplace Museum and the Birthplace Home; stage shows; picnics; dances; historical displays; plus the fellowship of hundreds of Miller fans from around the world.