Grant county is located in north central Oklahoma on the Kansas border with Medford serving as the county seat.
The Salt Fork of the Arkansas River in the southern portion of the county is the only "major" waterway.
The old Chisholm Trail (U.S. Highway 81) passes through the middle of the county in a north-south direction and was used to herd cattle to the stockyards in Kansas prior to the railroads coming in.
The handful of historic sites in the county include the Deer Creek General Merchandise Store, the Bank of Nashville in Nash and the Medford Bathhouse and Swimming Pool.
The county population on July 1, 1999, was 5,237, a decrease of 452 over the 1990 census.