St. Helena is located in Beaufort County. St. Helena is the largest community on St. Helena Island, connected by Highway 21 to Beaufort.
Fort Fremont is located at Lands End on St. Helena Island, S.C., four miles southeast of Port Royal. It overlooks the Fort Fremont Reach of the stretch of the Intracoastal Waterway that runs from Port Royal to the Beaufort River.
There is also a St. Helena, California.