Mathis is located just northwest of Corpus Christi on I-37 near Lake Corpus Christi.
Mathis is part of the Corpus Christi, Texas metro area.
The town was established in 1885, and is the commercial center for the area, featuring livestock and cotton, and large quantities of grain sorghum, flax, and varied truck crops. San Patricio County has extensive oil production, and many petrochemical plants.
Mathis is a major gateway to Lake Corpus Christi and to a popular state park on its shores.
In 1959 the Wesley Seale Dam raised the level of the lake to ninety-four feet above sea level and brought more lakeside development to enrich the town's economy. In 1988 Mathis had a population of 5,910. Probably twice that number lived around the lake. Ranching and farming form the basis for the economy, but tourism around the lake is important.
In 1990 the population was 5,423.