Cache River National Wildlife Refuge is located in the White River Basin of east central Arkansas, within commuting distance of Memphis, Tennessee and Little Rock, Arkansas. The refuge was established in 1986 with acquisition continuing on a willing seller basis within the 175,000 acre acquisition boundary. The refuge is identified in the North America Waterfowl Management Plan as the most important area in the Mississippi flyway for wintering mallards, and it has been identified as a Wetland of International Importance. Cache River Refuge is home to the only population of native black bear in Arkansas, and the largest population in the Mississippi alluvial valley.