Online Highways Home > Florida > Sanibel City Map with Features Caloosahatchee National Wildlife Refuge The Caloosahatchee NWR (Refuge), administered as a satellite refuge of J.N. "Ding" Darling NWR, is located in Lee County on the Caloosahatchee River, within the City of Ft. Myers. Originally, the Caloosahatchee Refuge consisted of several mangrove islands. However, shoreline development, dredging of the River, and construction of the I-75 bridge has changed the physical arrangement and appearance of these islands. Today, the Refuge still remains approximately 40 acres of mangrove shorelines and upland habitats - island habitat. The Refuge is located adjacent to the Florida Power and Light Company's Orange River Power Plant and the Orange River's out-flow. The warm water out-flow from the power plant is a major wintering area for the endangered West Indian Manatee. By boat, the refuge is located under the I-75 bridge as you head up the Caloosahatchee River. Read reviews and find hotels in Sanibel. Location: Fish and Wildlife Service, 1 Wildlife Dr, Sanibel Florida 33957 Telephone 941-472-1100 See more Wildlife Viewing. Other upcoming events include:

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