The Cache River rises in southern Illinois in
Union Countyand flows in a southeasterly direction until it reaches a point in
Johnson County near
Belknap where it turns south and then bends back to the west-southwest. Another change in direction occurs in western
Pulaski County where it takes a southern tack and finally breaks to the southeast before emptying into the
Ohio River just south of
Mound City. It is the last major tributary of the big river before it merges with the
Mississippi River.
