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The Saline River is located in southern Illinois and is 75.5 miles long, with tributaries that include the South, Middle and North Forks. Cities in the drainage area include
Marion
,
Harrisburg
,
Eldorado
,
Equality
and
Shawneetown
. The river, after passing through the eastern section of the
Shawnee National Forest
, empties into the
Ohio River
north of
Cave-in-Rock State Park
.