Online Highways Home > South Carolina > Santee Santee is located in Orangeburg County east of Orangeburg along Highway 6. The town is situated just off Interstate 95 in Orangeburg County, near Lake Marion. The Town of Santee and the surrounding area offer many amenities for both visitors and residents. There are many lodging accommodations, from full service motels to lake cabins. Santee also offers several dining options from tradition Southern home cooking to traditional barbecue. History and beauty abound in our five county region (Berkeley, Calhoun, Clarendon, Orangeburg and Sumter). There are museums, parks, flower gardens, plantation homes, nature trails, historic battle grounds, lake and river tours and much more. There are many sporting opportunities as well. Within a 45 minute drive of Santee, golfers can play 15, 18 holes courses. There is also a Santee, California. Golf Country Inn Suites Santee | Days Inn Santee | Howard Johnson Santee Sc | Ramada Santee | History Berkeley Museum | Fort Watson | Motels, Hotels and Resorts Best Western Santee | Best Western Santee Inn | Clarks Inn | Comfort Inn | Days Inn | Holiday Inn | Howard Johnson-Santee | Ramada Inn | Santee Economy Inn | Super 8 Santee SC | South Carolina State Parks Santee State Park | Sports and Sporting Events Hood's Guide Service | See more South Carolina Cities and Towns. The Most Anticipated Upcoming South Carolina Events Are: South Carolina Writers Workshop Conference Myrtle Beach continuing thru October 25 Western Carolina State Fair Aiken continuing thru October 31 Wooden Boat Show Georgetown continuing Other upcoming events include:

Search South Carolina 6 What have people been Tweeting about Santee?

martiniranch "drove our team tonight. We gave rides for the Tree Lighting Ceremony in Santee, CA. The horses were great. The... http://bit.ly/08JNVl5"
BoatLiftandDock "DFG taking close look at aquaculture permits: Lake Poway is the latest to gain an aquaculture permit. Santee La.. http://bit.ly/67BuU0"
achrisnaples "@rockhawkjohnny! Santee. :D"
MyersRealEstate "3br/2ba Condo/Townhome in Santee, CA 92071 for sale - $170,000 - Courtesy of Home Builders Marketing Servic http://bit.ly/78XXzv"
sd_shortsale "#ShortSale listed in #Santee, CA #92071 3br, $225K Quiet, peaceful and tranquil setting for thi.. http://sandiegodom.com/mls/090065265.aspx"
FreeListSD "Free Firewood/Pine (Santee): It's all yours. All you have to do is cut it down. Pretty big tree with pine needl.. http://bit.ly/078X7cj"
PenGwennsMom "Finally home after family fun at the Holiday Lighting Event in Santee! Awesome family fun! I LOVE OUR FAMILY AND OUR LIFE TOGETHER!!! :D"
justinmclachlan "I'm at Sonic #5995 (10515 Mission Gorge Rd, Magnolia Ave, Santee). http://bit.ly/3sRalz"
topix_sc "Public meeting for roads supporting Jafza project set for December - http://bit.ly/4R6xpd #Santee #SouthCarolina"
Check everything within 25 miles of Santee South Carolina