Online Highways Home > South Carolina > Switzer Switzer is located in Spartanburg County between Woodruff and Moore along Highway 221 on the banks of the Tyger River. Switzer is located a few miles from Interstate 26, south of Spartanburg in northwest South Carolina. Switzer is part of the Greenville-Spartanburg-Anderson metro area. History Walnut Grove | See more South Carolina Cities and Towns. The Most Anticipated Upcoming South Carolina Events Are: Wooden Boat Show Georgetown continuing Other upcoming events include:

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