Come stay at the Best Western apalach inn in apalachicola, land of the friendly people. We are located in the panhandle of florida, near the most beautiful and well preserved natural resources. Our pristine beaches and peaceful river make apalachicola a wonderful area for nature lovers. Apalachicola is famous for some of the best seafood in the country. Enjoy both fresh and salt water fishing, hunting, bird watching, historic walking tours and unique shops.60 miles east of panama city. Take interstate-10 to route 231 south to highway 98e; 3/4 mile before downtown apalachicola on left. 80 miles southwest of tallahassee. Take route 319 south to highway 98w.