Lake Alice National Wildlife Refuge is located in the eastern section of the Lakes and Gardens Region of North Dakota about 15 miles north of the west end of Devils Lake.

The 11,500-acre Refuge serves as a major waterfowl concentration point during spring and fall migrations, as well as a significant breeding area for wetland wildlife. Tens of thousands of snow geese, Canada geese, sandhill cranes, and ducks use the 3,500-acre lake and surrounding lands each year.

A birder's nirvana, wildlife includes a colony of Franklin gulls, rookeries of black-crowned night herons, snowy and cattle egrets, western and eared grebes, marsh wrens, Virginia and sora rails, coots, bitterns, and great blue herons.

For hunters, the Refuge supports populations of mallards, pintails, blue-winged teal, Hungarian partridge, ring-necked pheasant and sharp-tailed grouse.

A primitive camping area is located on the shore of nearby Chain Lake.