Texhoma is located in the Panhandle region of Oklahoma in Texas County about 20 miles southwest of Guymon along U.S. Highway 54 and SR 95 nearly abutting the Texas state line. The Beaver River enters the state from Texas about 5 miles west of town. Other significant water-based recreation can be found at Optima Lake and the Optima National Wildlife Refuge which are located about 15 miles east of Guymon.