Highway 75 is one of the main north-south routes across Eastern Oklahoma. From the Kansas border, it passes to the east of
Bartlesville and
Skiatook on its way to
Tulsa. From there it runs
Okmulgee where it becomes U.S. Highway 62/75. it intersects
Interstate 40 near
Henryetta becoming the Indian Nation Turnpike until just south of
McAlester merging with U.S. Highway 69 and turning in a southwesterly direction passing by
Atoka and
Durant before crossing the
Red River.
